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Sertaconazole Nitrate 2%
An imidazole antifungal agent.
Blocks synthesis of ergosterol by inhibiting the 14 a – demethylase enzyme.
Inhibition of ergosterol synthesis prevents fungal cells from multiplying & impairs hyphae growth.
Sertaconazole also has antiinflammatory, antibacterial and antipruritic action.
Inhibits the release of proinflammatory cytokines from activated immune cells.